Receptor Tyrosine Kinase

Blockade of Vascular Endothelial Growth Factor Signaling Ameliorates Diabetic Albuminuria in Mice

Nephrology / Oncology / Urology / Immunology / Cancer / Treatment / Immunohistochemistry / Femtosecond Laser / Cornea / Immunology of the Gut / Near Infrared / Apoptosis / Pancreatic Cancer / Multidisciplinary / Cancer treatment / Photodynamic Therapy / Cell Division / Signal Transduction / High Frequency / Microvascular Physiology / Complication / Humans / Cancer Therapy / Lasers / Epidermal Growth Factor/ErbB receptors / Reactive Oxygen Species / Mice / Stress response / Animals / Male / Squamous Cell Carcinoma / Vascular endothelium / Protein Tyrosine Kinase / Fibroblast Growth Factor / Diabetic Nephropathy / Clinical Sciences / Spectrum / Epidermal Growth Factor / Epidermal Growth Factor Receptor / Optometry and Ophthalmology / Tyrosine Kinase Inhibitor / Photochemotherapy / Endothelial cell / Public health systems and services research / Model System / Neoplasms / Pyridines / Kidney Disease / Circulation / Blood Vessels / Ionizing Radiation / Lymph Node / Type 2 Diabetes Mellitus / Antitumor Activity / Growth Factor / Vascular Endothelial Function / Glomerular Basement Membrane / High Spatial Resolution / Blood Vessel / Lymphatic System / Nude mice / Neutralizing antibodies / Vascular Endothelial Growth Factor / Tyrosine Kinase / Vascular endothelial growth factor receptor / Receptor Tyrosine Kinase / Phthalazines / Treatment / Immunohistochemistry / Femtosecond Laser / Cornea / Immunology of the Gut / Near Infrared / Apoptosis / Pancreatic Cancer / Multidisciplinary / Cancer treatment / Photodynamic Therapy / Cell Division / Signal Transduction / High Frequency / Microvascular Physiology / Complication / Humans / Cancer Therapy / Lasers / Epidermal Growth Factor/ErbB receptors / Reactive Oxygen Species / Mice / Stress response / Animals / Male / Squamous Cell Carcinoma / Vascular endothelium / Protein Tyrosine Kinase / Fibroblast Growth Factor / Diabetic Nephropathy / Clinical Sciences / Spectrum / Epidermal Growth Factor / Epidermal Growth Factor Receptor / Optometry and Ophthalmology / Tyrosine Kinase Inhibitor / Photochemotherapy / Endothelial cell / Public health systems and services research / Model System / Neoplasms / Pyridines / Kidney Disease / Circulation / Blood Vessels / Ionizing Radiation / Lymph Node / Type 2 Diabetes Mellitus / Antitumor Activity / Growth Factor / Vascular Endothelial Function / Glomerular Basement Membrane / High Spatial Resolution / Blood Vessel / Lymphatic System / Nude mice / Neutralizing antibodies / Vascular Endothelial Growth Factor / Tyrosine Kinase / Vascular endothelial growth factor receptor / Receptor Tyrosine Kinase / Phthalazines

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Fluorescence energy transfer detection as a homogeneous DNA diagnostic method

Cystic Fibrosis / Fluorescence / Membrane Proteins / Multidisciplinary / Humans / Mutation / Mutation Detection / Genome Analysis / Real Time / Genotype / Very high throughput / Energy Transfer / Receptor Tyrosine Kinase / Mutation / Mutation Detection / Genome Analysis / Real Time / Genotype / Very high throughput / Energy Transfer / Receptor Tyrosine Kinase

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met oncogene activation qualifies spontaneous canine osteosarcoma as a suitable pre&hyphen;clinical model of human osteosarcoma

Pathology / Cancer / Immunohistochemistry / Enzyme Inhibitors / RNA interference / Dogs / Humans / Models / Animals / Osteosarcoma / The / Clinical Sciences / Neoplasm Invasiveness / Antineoplastic Agents / Receptor Tyrosine Kinase / Dogs / Humans / Models / Animals / Osteosarcoma / The / Clinical Sciences / Neoplasm Invasiveness / Antineoplastic Agents / Receptor Tyrosine Kinase

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PDGF signal transduction inhibition ameliorates experimental mesangial proliferative glomerulonephritis1

Enzyme Inhibitors / Extracellular Matrix / Cell Division / Signal Transduction / Cell line / Smooth muscle / Kidney / Collagen / Animals / Male / Fibroblast Growth Factor / Clinical Sciences / Rats / Wistar Rats / Cell Proliferation / Growth Factor / Renal disease / Benzamides / Receptor Tyrosine Kinase / Smooth muscle / Kidney / Collagen / Animals / Male / Fibroblast Growth Factor / Clinical Sciences / Rats / Wistar Rats / Cell Proliferation / Growth Factor / Renal disease / Benzamides / Receptor Tyrosine Kinase

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Vascular endothelial growth factor mediated angiogenic potential of pancreatic ductal carcinomas enhanced by hypoxia: Anin vitro andin vivo study

Pathology / Surgery / Molecular Biology / Cancer / Wound Healing / Humans / Mice / Tyrosine Kinase Receptor / Animals / Male / Fibroblast Growth Factor / Behavioral Animal Models / Clinical Sciences / Rats / Endothelial cell / Rat / Blood Flow / Ovarian Carcinoma / Protein isoforms / ENDOTHELIUM / Surgical / Murine Model / Tensile Strength / Lung Carcinoma / Vascular Endothelial Growth Factor / Tyrosine Kinase / Receptor Tyrosine Kinase / Humans / Mice / Tyrosine Kinase Receptor / Animals / Male / Fibroblast Growth Factor / Behavioral Animal Models / Clinical Sciences / Rats / Endothelial cell / Rat / Blood Flow / Ovarian Carcinoma / Protein isoforms / ENDOTHELIUM / Surgical / Murine Model / Tensile Strength / Lung Carcinoma / Vascular Endothelial Growth Factor / Tyrosine Kinase / Receptor Tyrosine Kinase

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Neuroblastoma-targeted Nanoparticles Entrapping siRNA Specifically Knockdown ALK

Technology / Nanoparticles / Gene Silencing / Western blotting / Biological Sciences / Molecular / RNA interference / Cell line / Humans / Mice / Animals / Cell Death / Neuroblastoma / Delivery System / Anaplastic Lymphoma Kinase (ALK) / Transfection / Side Effect / Antitumor Activity / Molecular Targeted Therapy / Receptor Tyrosine Kinase / Cell Growth / Molecular / RNA interference / Cell line / Humans / Mice / Animals / Cell Death / Neuroblastoma / Delivery System / Anaplastic Lymphoma Kinase (ALK) / Transfection / Side Effect / Antitumor Activity / Molecular Targeted Therapy / Receptor Tyrosine Kinase / Cell Growth

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PDGF signal transduction inhibition ameliorates experimental mesangial proliferative glomerulonephritis1

Enzyme Inhibitors / Extracellular Matrix / Cell Division / Signal Transduction / Cell line / Smooth muscle / Kidney / Collagen / Animals / Male / Fibroblast Growth Factor / Clinical Sciences / Rats / Wistar Rats / Cell Proliferation / Growth Factor / Renal disease / Benzamides / Receptor Tyrosine Kinase / Smooth muscle / Kidney / Collagen / Animals / Male / Fibroblast Growth Factor / Clinical Sciences / Rats / Wistar Rats / Cell Proliferation / Growth Factor / Renal disease / Benzamides / Receptor Tyrosine Kinase

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Alkynyl pyrimidines as dual EGFR/ErbB2 kinase inhibitors

Organic Chemistry / Medicinal Chemistry / Macromolecular X-Ray Crystallography / Humans / Kinase inhibitor / Hydrogen Bond / Bioorganic and medicinal Chemistry / Cell Proliferation / Structure activity Relationship / Alkynes / Molecular Structure / Receptor Tyrosine Kinase / Hydrogen Bond / Bioorganic and medicinal Chemistry / Cell Proliferation / Structure activity Relationship / Alkynes / Molecular Structure / Receptor Tyrosine Kinase

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Neuroblastoma-targeted Nanoparticles Entrapping siRNA Specifically Knockdown ALK

Pharmacology / Technology / Nanoparticles / Gene Silencing / Western blotting / Biological Sciences / Molecular / RNA interference / Cell line / Humans / Mice / Animals / Therapy / Cell Death / Neuroblastoma / Delivery System / Anaplastic Lymphoma Kinase (ALK) / Transfection / Side Effect / Antitumor Activity / Molecular Targeted Therapy / Receptor Tyrosine Kinase / Cell Growth / Biological Sciences / Molecular / RNA interference / Cell line / Humans / Mice / Animals / Therapy / Cell Death / Neuroblastoma / Delivery System / Anaplastic Lymphoma Kinase (ALK) / Transfection / Side Effect / Antitumor Activity / Molecular Targeted Therapy / Receptor Tyrosine Kinase / Cell Growth

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Semirational design of a potent, artificial agonist of fibroblast growth factor receptors

Clinical Trial / Multidisciplinary / Nature / Protein Design / Phage display / Fibroblast Growth Factor / Peripheral Vascular Disease / Receptor Tyrosine Kinase / Fibroblast Growth Factor / Peripheral Vascular Disease / Receptor Tyrosine Kinase

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Blockade of Vascular Endothelial Growth Factor Suppresses Experimental Restenosis After Intraluminal Injury by Inhibiting Recruitment of Monocyte Lineage Cells

Nephrology / Oncology / Urology / Immunology / Cancer / Treatment / Immunohistochemistry / Cornea / Immunology of the Gut / Apoptosis / Pancreatic Cancer / Multidisciplinary / Cell Division / Signal Transduction / Microvascular Physiology / Complication / Humans / Cancer Therapy / Lasers / Epidermal Growth Factor/ErbB receptors / Reactive Oxygen Species / Mice / Stress response / Animals / Male / Squamous Cell Carcinoma / Immunotherapy / Vascular endothelium / Protein Tyrosine Kinase / Fibroblast Growth Factor / Diabetic Nephropathy / Clinical Sciences / Epidermal Growth Factor Receptor / Optometry and Ophthalmology / Tyrosine Kinase Inhibitor / Photochemotherapy / Endothelial cell / Public health systems and services research / Model System / Neoplasms / Pyridines / Kidney Disease / Circulation / Blood Vessels / Albuminuria / Ionizing Radiation / Lymph Node / Type 2 Diabetes Mellitus / Antitumor Activity / Growth Factor / Vascular Endothelial Function / Glomerular Basement Membrane / Blood Vessel / Protein Kinase Inhibitors / Lymphatic System / Nude mice / Neutralizing antibodies / Gene Transfer / Vascular Endothelial Growth Factor / Vascular endothelial growth factor receptor / Receptor Tyrosine Kinase / Phthalazines / Treatment / Immunohistochemistry / Cornea / Immunology of the Gut / Apoptosis / Pancreatic Cancer / Multidisciplinary / Cell Division / Signal Transduction / Microvascular Physiology / Complication / Humans / Cancer Therapy / Lasers / Epidermal Growth Factor/ErbB receptors / Reactive Oxygen Species / Mice / Stress response / Animals / Male / Squamous Cell Carcinoma / Immunotherapy / Vascular endothelium / Protein Tyrosine Kinase / Fibroblast Growth Factor / Diabetic Nephropathy / Clinical Sciences / Epidermal Growth Factor Receptor / Optometry and Ophthalmology / Tyrosine Kinase Inhibitor / Photochemotherapy / Endothelial cell / Public health systems and services research / Model System / Neoplasms / Pyridines / Kidney Disease / Circulation / Blood Vessels / Albuminuria / Ionizing Radiation / Lymph Node / Type 2 Diabetes Mellitus / Antitumor Activity / Growth Factor / Vascular Endothelial Function / Glomerular Basement Membrane / Blood Vessel / Protein Kinase Inhibitors / Lymphatic System / Nude mice / Neutralizing antibodies / Gene Transfer / Vascular Endothelial Growth Factor / Vascular endothelial growth factor receptor / Receptor Tyrosine Kinase / Phthalazines

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Tumor Endothelium-specific Transgene Expression Directed by Vascular Endothelial Growth Factor Receptor2 (Flk-1) Promoter/Enhancer Sequences1,2

Cancer / Gene expression / Transgenic Mice / Epidermal Growth Factor/ErbB receptors / Mice / Female / Animals / Male / Vascular endothelium / Fibrosarcoma / Specific Activity / Transgene Expression / Blood Vessel / Adenocarcinoma / Vascular endothelial growth factor receptor / Receptor Tyrosine Kinase / Female / Animals / Male / Vascular endothelium / Fibrosarcoma / Specific Activity / Transgene Expression / Blood Vessel / Adenocarcinoma / Vascular endothelial growth factor receptor / Receptor Tyrosine Kinase

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